diff --git a/UI/Settings/Quality/Profile/QualityProfileView.js b/UI/Settings/Quality/Profile/QualityProfileView.js
index 9dd7d429f..854520a24 100644
--- a/UI/Settings/Quality/Profile/QualityProfileView.js
+++ b/UI/Settings/Quality/Profile/QualityProfileView.js
@@ -6,17 +6,20 @@ define(
         'marionette',
         'Settings/Quality/Profile/EditQualityProfileView',
         'Settings/Quality/Profile/DeleteView',
+        'Series/SeriesCollection',
         'Mixins/AsModelBoundView',
-        'Settings/Quality/Profile/AllowedLabeler'
+        'Settings/Quality/Profile/AllowedLabeler',
+        'bootstrap',
 
-    ], function (App, Marionette, EditProfileView, DeleteProfileView, AsModelBoundView) {
+    ], function (App, Marionette, EditProfileView, DeleteProfileView, SeriesCollection, AsModelBoundView) {
 
         var view = Marionette.ItemView.extend({
             template: 'Settings/Quality/Profile/QualityProfileTemplate',
             tagName : 'li',
 
             ui: {
-                'progressbar': '.progress .bar'
+                'progressbar' : '.progress .bar',
+                'deleteButton': '.x-delete'
             },
 
             events: {
@@ -26,6 +29,7 @@ define(
 
             initialize: function () {
                 this.listenTo(this.model, 'sync', this.render);
+                this.listenTo(SeriesCollection, 'all', this._updateDisableStatus)
             },
 
             _editProfile: function () {
@@ -34,8 +38,32 @@ define(
             },
 
             _deleteProfile: function () {
+                if (this._isQualityInUse()) {
+                    return;
+                }
+
                 var view = new DeleteProfileView({ model: this.model });
                 App.modalRegion.show(view);
+            },
+
+            onRender: function () {
+                this._updateDisableStatus();
+            },
+
+            _updateDisableStatus: function () {
+                if (this._isQualityInUse()) {
+                    this.ui.deleteButton.addClass('disabled');
+                    this.ui.deleteButton.attr('title', 'Can\'t delete quality profiles attached to a series.');
+                }
+                else {
+                    this.ui.deleteButton.removeClass('disabled');
+                    this.ui.deleteButton.attr('title', 'Delete Quality Profile');
+                }
+            },
+
+            _isQualityInUse: function () {
+                return SeriesCollection.where({'qualityProfileId': this.model.id}).length !== 0;
+
             }
         });